Epileptic seizures in systemic lupus erythematosus. The histological hallmark of SLE is membranous glomerulonephritis with "wire loop" abnormalities. Raynaud's phenomenon occurs in one third of patients at the onset of SLE. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures.
Bone tissue death avascular necrosis.
This material may present a threat to the tolerization of B cells and T cells. Arthralgia, myalgia, and frank arthritis may involve the small joints of the hands, wrists, and knees.
The general symptoms are not specific.
Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus. Transudation of fluid through Bruch's membrane may result in multifocal retinal pigment epithelium RPE and serous retinal detachments.
Renal failure and sepsis are two main causes of death in patients with SLE. The most common infections involve the respiratory tract, urinary tract, and skin and do not require hospitalization if they are treated promptly.
Lupus panniculitis as an initial manifestation of systemic lupus erythematosus. In healthy conditions, apoptotic lymphocytes are removed in germinal centers GC by specialized phagocytes, the tingible body macrophages TBMwhich is why no free apoptotic and potential autoantigenic material can be seen.